Starts 27 Apr 2021 15:00
Ends 27 Apr 2021 16:00
Central European Time
QLS Seminar: Rulers, timers and transport for length control in long cell protrusions
Zoom Meeting
Join Zoom Meeting https://zoom.us/j/475819702
Meeting ID: 475-819-702
If you haven't registered for previous QLS webinars, please contact qls@ictp.it to obtain the PASSWORD for this zoom meeting.
Abstract:
A living cell uses its long cylindrical appendages for locomotion and sensory purposes. Therefore, assembling and maintaining a protrusion of correct length is crucial for its survival and overall performance. Usually the protrusions lack the machinery for the synthesis of building blocks and imports them from the cell body.
What are the unique features of the transport logistics which facilitate the exchange of these building blocks between the cell and the protrusion? What kind of ‘rulers’ and ‘timers’ does the cell use for constructing its appendages of correct length? How do the multiple appendages coordinate and communicate among themselves during different stages of their existence? How frequently do the fluctuations drive the length of these dynamic protrusions out of the acceptable bounds?
In this talk, I'll present an overview of our theoretical models that address these questions in the context of eukaryotic flagella.
Meeting ID: 475-819-702
If you haven't registered for previous QLS webinars, please contact qls@ictp.it to obtain the PASSWORD for this zoom meeting.
Abstract:
A living cell uses its long cylindrical appendages for locomotion and sensory purposes. Therefore, assembling and maintaining a protrusion of correct length is crucial for its survival and overall performance. Usually the protrusions lack the machinery for the synthesis of building blocks and imports them from the cell body.
What are the unique features of the transport logistics which facilitate the exchange of these building blocks between the cell and the protrusion? What kind of ‘rulers’ and ‘timers’ does the cell use for constructing its appendages of correct length? How do the multiple appendages coordinate and communicate among themselves during different stages of their existence? How frequently do the fluctuations drive the length of these dynamic protrusions out of the acceptable bounds?
In this talk, I'll present an overview of our theoretical models that address these questions in the context of eukaryotic flagella.