A tumor is a complex ecosystem with a myriad of bio-physical and -chemical effects operative over varying time and length scales – from genetic/non-genetic changes in cells during cancer initiation to colonization of distant organs and resurgence of tumor after therapy. While it has been largely been studied from a reductionist and descriptive molecular perspective, recent advancements in experimental tools have enabled mapping systems-level spatiotemporal changes with high precision and thus attracted the attention of physicists, mathematicians, and engineers. However, developing concerted theoretical frameworks to make testable predictions for disease progression is still in its infancy. Participants will be exposed to the latest open questions in the field and experience an intellectual cross-fertilization of research ideas in terms of applying different models to better predict cancer progression dynamics.
Topics:
- Stochastic cell-fate decisions in cancer
- Cellular cooperation and competition in cancer
- Cell mechanics and soft matter aspects in cancer
- Emergent dynamics of tumor-stroma interactions and co-evolution
Speakers:
N. Balasubramanian, IISER Pune, India
R. Bhat, IISc Bangalore, India
D. Bi, Northeastern University, USA
H. Byrne, Oxford University, UK
S. Chakrabarti, NCBS Bangalore, India
F. Eduati, TU Eindhoven, Netherlands
J. George, Texas A&M University, USA
M. Jolly, IISc Bangalore, India
R. Laubenbacher, University of South Florida, USA
C. La Porta, University of Milan, Italy
T. Lele, Texas A&M University, USA
K. Miroshnikova, Max Planck Institute for Molecular Biomedicine, Germany
A. Puliafito, University of Torino, Italy
E. Regan, Wooster College, USA
S. Sen, IIT Bombay, India
V. Shenoy, University of Pennsylvania, USA
S. Singh, National Institute of Biomedical Genomics, India
K. Tanner, NIH, USA
M. Vishwakarma, IISc Bangalore, India
Grants: A limited number of grants are available to support the attendance of selected participants, with priority given to participants from developing countries. There is no registration fee.