In the last ten years the field of cognitive neuroscience has experienced enormous growth, partially in the development of brain imaging techniques. In particular, many investigators have begun to focus research on understanding how the brain implements the cognitive control of behaviour and the intergral functions. This Workshop will bring together leading researchers who are active in different disciplines and fields such as Neuropsychology, Brain Inaging, Mathematical Modeling and Computer Science, with an interest in the understanding of high order cognitive functions of the prefrontal cortex such as attention, working memory and executive processes. The aim of the Workshop will be to contribute to the elaboration coordinated approach to understanding prefrontal functions that integrate current experimental data theoretical models.