The depletion attraction and its role in the physical behaviour of crowded macromolecular systems
Starts 12 Feb 2016 11:00
Ends 12 Feb 2016 12:00
Central European Time
Central Area, 2nd floor, old SISSA building
In this talk, I will review the physics of the depletion interaction, demonstrating how it can profoundly influence the properties of several systems at the interface between bio- and soft-matter physics. This mechanism of “attraction through repulsion”, quite general in multi-component systems where different species intermingle and mutually exclude their volumes, will be proved to be the key determinant of the complex phase behaviour of colloid-polymer mixtures  as well as the responsible for a dramatic change in the conformational and self-entanglement properties of a macromolecule in a crowded environment . To this end, I will also present and discuss some efficient and rigorous coarse-graining methodologies  which, retaining only the relevant degrees of freedom, allow to explore the large-scale behaviour of these systems while reducing their complexity from a computational perspective.
G. D’Adamo, A. Pelissetto and C. Pierleoni, J. Chem. Phys. 141, 024902 (2014).
G. D’Adamo and C. Micheletti, Macromolecules 48, 6337 (2015)
G. D’Adamo, A. Pelissetto and C. Pierleoni, Soft Matter, 8, 5151 (2011).
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