Description |
Recently developed free-energy methods (steered molecular dynamics, well-tempered metadynamics, parallel tempering and solute tempering) will be discussed, and their application to the folding of small proteins and RNA molecules will be shown. Using these techniques, a proposed model for RNA unwinding is validated and interpreted at atomistic resolution. |
Informal seminar on Statistical Physics: "Accelerated sampling of the conformational space in biomolecules: From small proteins to RNAs"
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